Bengt Mannervik Selected Research

TER 286 (TLK286)

11/2013

Mechanism of glutathione transferase P1-1-catalyzed activation of the prodrug canfosfamide (TLK286, TELCYTA).

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Bengt Mannervik Research Topics

Disease

14	Neoplasms (Cancer) 10/2021 - 01/2002
2	Parkinson Disease (Parkinson's Disease) 04/2021 - 02/2019
2	Glioblastoma (Glioblastoma Multiforme) 04/2015 - 04/2014
2	Inflammation (Inflammations) 03/2015 - 08/2004
1	Neuroinflammatory Diseases 01/2022
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2022
1	Neuroblastoma 04/2021
1	Communicable Diseases (Infectious Diseases) 10/2015
1	Asthma (Bronchial Asthma) 09/2015
1	Hypersensitivity (Allergy) 03/2015
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2014
1	Breast Neoplasms (Breast Cancer) 11/2013
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 11/2013
1	Ovarian Neoplasms (Ovarian Cancer) 11/2013
1	Hodgkin Disease (Hodgkin's Disease) 01/2011
1	Nasal Polyps (Nasal Polyp) 01/2011
1	Autoimmune Diseases (Autoimmune Disease) 07/2010
1	Colitis 08/2004
1	Malaria 02/2002

Drug/Important Bio-Agent (IBA)

9	O-(glucuronic acid 2-sulfate)-(1--3)-O-(2,5)-andydrotalitol 6-sulfateIBA 10/2021 - 02/2002
5	Glutathione Transferase (Glutathione S-Transferase)IBA 04/2015 - 08/2004
4	ProdrugsIBA 10/2021 - 06/2007
4	EnzymesIBA 04/2021 - 04/2015
4	aminochrome 1 (aminochrome)IBA 04/2021 - 04/2014
2	alpha-SynucleinIBA 01/2022 - 02/2019
2	Azathioprine (Imuran)FDA LinkGeneric 01/2014 - 07/2010
2	Alkylating AgentsIBA 11/2013 - 02/2002
1	neuromelaninIBA 01/2022
1	diazeniumdiolateIBA 10/2021
1	NeurotoxinsIBA 04/2021
1	glutathione S-transferase Mu 2IBA 04/2021
1	Octoxynol (Triton X 100)IBA 12/2016
1	Pharmaceutical PreparationsIBA 10/2015
1	Arachidonate 15-Lipoxygenase (Arachidonate 15 Lipoxygenase)IBA 09/2015
1	Glutathione (Reduced Glutathione)IBA 04/2015
1	prostaglandin R2 D-isomerase (prostaglandin D2 synthase)IBA 03/2015
1	Prostaglandin D2IBA 03/2015
1	Prostaglandin H2 (PGH(2))IBA 03/2015
1	TER 286 (TLK286)IBA 11/2013
1	Cytostatic AgentsIBA 09/2013
1	Glutathione S-Transferase piIBA 09/2013
1	AcidsIBA 01/2011
1	Arachidonic Acid (Vitamin F)IBA 01/2011
1	13-hydroxy-9,11-octadecadienoic acidIBA 07/2006
1	AntibodiesIBA 08/2004
1	CarrageenanIBA 08/2004
1	Dextran SulfateIBA 08/2004
1	isothiocyanic acidIBA 06/2003
1	Antineoplastic Agents (Antineoplastics)IBA 02/2002
1	Proteins (Proteins, Gene)FDA Link 02/2002
1	Quinidine (Chinidin)FDA LinkGeneric 02/2002
1	Quinine (Quinson)FDA Link 02/2002
1	Tetracycline (Achromycin)FDA LinkGeneric 02/2002
1	Antimalarials (Antimalarial Agents)IBA 02/2002
1	artemisinin (artemisinine)IBA 02/2002

Therapy/Procedure

6	Drug Therapy (Chemotherapy) 10/2021 - 01/2002
1	Organ Transplantation 07/2010
1	Therapeutics 02/2002